Microbiology The most sensitive test for the diagnosis of herpes simplex (HSV) meningitis in a newborn infant is A HSV IgG antibody B HSV polymerase chain reaction (PCR) C HSV culture D Tzanck smear 💡 Explanation The most sensitive test for the diagnosis of herpes simplex (HSV) meningitis in a newborn infant is ✓ Correct Answer: B. HSV polymerase chain reaction (PCR)