Pharmacology The most potent topical coicosteroid is: A Hydrocoison butyrate cream 0.1% B Betamethasone Valerate cream 0.1% C Clobetasol propionate cream 0.5% D Clobetasone butyrate cream 0.5% 💡 Explanation The most potent topical coicosteroid is: ✓ Correct Answer: B. Betamethasone Valerate cream 0.1%