Surgery The most commonly used drug in the immunosuppression of renal transplant patients is cyclosporine. A major side effect of this drug is: A Pancytopenia B Constipation C Nephrotoxicity D Amenorrhea 💡 Explanation The most commonly used drug in the immunosuppression of renal transplant patients is cyclosporine. A major side effect of this drug is: ✓ Correct Answer: C. Nephrotoxicity