## **Core Concept**
Candesartan is an **angiotensin II receptor antagonist (ARB)** used primarily to treat **hypertension** and **heart failure**. It works by blocking the action of angiotensin II at its receptor, thereby relaxing blood vessels and reducing blood pressure.

## **Why the Correct Answer is Right**
The correct dosage of Candesartan to begin with is crucial for managing side effects and achieving therapeutic efficacy. Starting with a low dose helps to minimize potential side effects such as **dizziness** and **hypotension**. The typical starting dose of Candesartan is **2 mg** once daily, which can be adjusted based on the patient's response and tolerance.

## **Why Each Wrong Option is Incorrect**
* **Option A:** - This option suggests a higher dose, which might not be suitable as a starting dose due to increased risk of side effects.
* **Option B:** - This option suggests an even higher dose, which is definitely not a starting dose.
* **Option D:** - This option suggests the highest dose among the options, which is not appropriate for initiating therapy.

## **Clinical Pearl / High-Yield Fact**
A key point to remember is that when initiating therapy with Candesartan or any antihypertensive agent, it's essential to monitor the patient's blood pressure and renal function closely, especially if the patient is on **diuretics** or has **renal impairment**. Also, remember that ARBs like Candesartan are **contraindicated in pregnancy** due to the risk of fetal harm.

## **Correct Answer:** .