Pathology The mechanism of the development of Acute Rheumatic Fever is which of the following? A Cross reactivity with exogenous antigen B Innocent bystander effect C Due to toxin secretion by streptococci D Release of pyrogenic cytokines 💡 Explanation The mechanism of the development of Acute Rheumatic Fever is which of the following? ✓ Correct Answer: A. Cross reactivity with exogenous antigen