Anatomy The mechanism of anti cancer action of fluoruracil is A Cross linking of double standard DNA and the resulting inhibition of DNA replication and transcription B Cytotoxicity resulting from metabolite that interferes with the production of dTMP C Irreversible inhibition of dihydrofolic acid reductase D Selective action of DNA polymerase π‘ Explanation The mechanism of anti cancer action of fluoruracil is β Correct Answer: C. Irreversible inhibition of dihydrofolic acid reductase