Biochemistry The mechanism of action of uncouplers of oxidative phosphorylation involves: A Inhibition of ATP synthase B Stimulation of ATP synthase C Disruption of proton gradient across the inner membrane D Disruption of proton gradient across outer membrane 💡 Explanation The mechanism of action of uncouplers of oxidative phosphorylation involves: ✓ Correct Answer: C. Disruption of proton gradient across the inner membrane