Pharmacology The mechanism of action of tetracyclines involves: A Binding of a component of the 50S ribosomal subunits B Inhibition of translocase activity C Blockade of binding of aminoacyl-tRNA to bacterial ribosomes by binding to 30S ribosome D Selective inhibition of ribosomal peptidyl transferase 💡 Explanation The mechanism of action of tetracyclines involves: ✓ Correct Answer: C. Blockade of binding of aminoacyl-tRNA to bacterial ribosomes by binding to 30S ribosome