Pharmacology The mechanism of action of tetracyclines involves : A Binding of a component of the 50S ribosomal subunits B Inhibition of translocase activity C Blockade of binding of aminoacyl–tRNA to bacterial ribosomes D Selective inhibition of ribosomal peptidyl transferase 💡 Explanation The mechanism of action of tetracyclines involves : ✓ Correct Answer: C. Blockade of binding of aminoacyl–tRNA to bacterial ribosomes