**Core Concept:**
The question is asking about the distribution of sodium in the human body, specifically focusing on which compartment holds the majority of body sodium. Understanding the distribution of sodium is crucial for understanding fluid balance, osmoregulation, and the overall function of sodium in the body.

**Why the Correct Answer is Right:**
The correct answer, Option C (Sodium is predominantly found in extracellular fluid), highlights the primary location where sodium is stored in the human body. Extracellular fluid (ECF) is the fluid outside of cells, making up about 20% of our body weight and containing 90% of the total sodium content in the body. This compartment is essential for maintaining osmoregulation, fluid balance, and cellular function.

**Why Each Wrong Option is Incorrect:**

A. Intracellular fluid (ICF) is incorrect because it is a smaller compartment (10% of body weight) and holds less sodium.
B. Blood plasma is a part of extracellular fluid, not a separate compartment.
D. The liver, kidneys, and other organs do not account for the majority of sodium storage.

**Clinical Pearl / High-Yield Fact:**
Understanding the distribution of sodium in the body can help in recognizing clinical conditions involving sodium imbalances, like hyponatremia (low sodium) or hypernatremia (high sodium), which can lead to severe complications if not managed appropriately.

**Correct Answer:** Option C: Sodium is predominantly found in extracellular fluid (ECF).