Pathology The interaction of histamine with its H2 receptor in the parietal cell results in A An increase in intracellular sodium concentration B An increase in intracellular cAMP production C An increase in intracellular cGMP production D A decrease in intracellular calcium concentration π‘ Explanation The interaction of histamine with its H2 receptor in the parietal cell results in β Correct Answer: B. An increase in intracellular cAMP production