Pediatrics The genetic mutation most commonly linked with congenital central hypoventilation syndrome is: A Mutation in sodium channel alpha 1 subunit B Mutation in paired like homeobox 2B gene C Mutation in outer dynein arm D All of the above 💡 Explanation The genetic mutation most commonly linked with congenital central hypoventilation syndrome is: ✓ Correct Answer: B. Mutation in paired like homeobox 2B gene