The following technique is used to analyze DNA obtained from cancer biopsies, in which tumor cells are often contaminated with large numbers of admixed stromal cells
Correct Answer: Pyrosequencing
Description: Ans. (c) Pyrosequencing(Ref: R 9th/pg 140; 8th/pg 140)Pyrosequencing:Highly sensitive than Sanger sequencing and can detect even 5% mutated DNAFor this reason, it is be used to analyze DNA obtained from cancer biopsies, in which tumor cells are often "contaminated" with large numbers of admixed stromal cells.
Category:
Pathology
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