Surgery The following statements regarding tissue plasminogen activator are true, except: A It is produced by recombinant DNA technology. B Induction of systemic lytic state is limited with its use. C It is ineffective in lysing thrombi of myocardial infarction. D It is a poor plasminogen activator in the absence of fibrin. 💡 Explanation The following statements regarding tissue plasminogen activator are true, except: ✓ Correct Answer: C. It is ineffective in lysing thrombi of myocardial infarction.