clear cell adenocarcinoma of vagina: Found in adolescent girls who have a history of intrauterine exposure to diethylstilbestrol Incidence following DES exposure is 1:1000 may develop vaginal adenosis lesion usually involves upper third of anterior vaginal wall and cervix may be involved Treatment: radical hysterectomy,vaginectomy with pelvic lymphadenectomy. D.C.DUTTA'S TEXTBOOKOF GYNECOLOGY,Pg no:339,6th edition