Biochemistry The following methods can be used to detect the point mutation in the beta (β)-globin gene that causes sickle cell anemia, except – A Polymerase chain reaction with allele-specific oligonucleotide hybridization B Southern blot analysis C DNA sequencing D Northern blot analysis 💡 Explanation The following methods can be used to detect the point mutation in the beta (β)-globin gene that causes sickle cell anemia, except - ✓ Correct Answer: D. Northern blot analysis