The following is not a pyrogenic cytokine
Correct Answer: Substance P
Description: Ans. (c) Substance P(Ref: J Infect Dis. (1999) 179 (Supplement 2): S294-S304. doi: 10.1086/513856, Harrison 18th ed:2666.)IL1 AND TNF are well known pyrogenic cytokines In the hypothalamus, the prostaglandins, especially PGE2, stimulate the production of neurotransmitters that reset the temperature set point at a higher level, hence pyrogenic
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