The following are predisposing factors for esophageal Ca Except –
Correct Answer: Benzene therapy
Description: Predisposing factors for Ca Esophagus
For Adenocarcinoma
Chronic gastric reflux (i,e Barrett's esophagus)
For Squamous cell Ca
Alcohol
Cigarette
Mucosal damage from physical agents → Hot tea, Lye ingestion, Radiation-induced strictures, Chronic achalasia
Other ingested carcinogens → Nitrates, Smoked opiates, Fungal toxins in pickled vegetables
Plummer -Vinson - Paterson Kelly syndrome ( Esophageal Web + glossitis + Iron deficiency )
Tylosis palmaris et plantaris ( Congenital hyperkeratosis and pitting of palms and soles)
Dietary deficiencies of molybdenum, Zinc, Vitamin A.
Celiac sprue
Chronic Achalasia
Following information has been added in 8th/e of Robbins
Human papillomavirus (HPV) infection has also been implicated in esophageal squamous cell carcinoma in high-risk areas but not in low-risk regions.
Category:
Pathology
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