Physiology The first step for lymphatic vessels to remove excess fluid from interstitial tissue spaces is by: A Generating a lower intravascular than tissue hydrostatic pressure B Contracting and forcing lymph into larger lymphatics C Opening and closing one-way valves in the lymph vessels D Lowering the colloid osmotic pressure inside the lymph vessel 💡 Explanation The first step for lymphatic vessels to remove excess fluid from interstitial tissue spaces is by: ✓ Correct Answer: A. Generating a lower intravascular than tissue hydrostatic pressure