The factor/mechanism involved in glomerulotubular balance is:
Correct Answer: Oncotic pressure in peritubular capillaries
Description: G-T balance refers to the mechanism by which increase in GFR and filtration of Na+ propoionately increases the Na+ (and water) reabsorption. Thus, a constant fraction (67%) of the filtered Na+ and water is reabsorbed from PCT, despite fluctuations in GFR. Mechanism: ~ Increased GFR (and increased filtered load of Na+& water) a increased protein concentration in the glomerular capillary plasma (as the fluid has been filtered out of this plasma) Protein-rich plasma leaves the glomerular capillaries efferent aerioles and enters the peritubular capillaries Colloid Oncotic pressure will increase in peritubular capillaries a increased the solute and water reabsorption by the PCT. Options A & C are involved in tubuloglomerular feedback. Sluggish blood flow in medullary interstitium is the basis for countercurrent exchange by vasa recta.
Category:
Physiology
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