The expression of the following oncogene is associated with a high incidence of medullary carcinoma of the thyroid
Correct Answer: Ret proto-oncogene
Description: MTC occurs most commonly in a sporadic form (80%); it occurs less commonly as an autosomal dominant inherited disorder such as MEN2A, MEN2B, and familial medullary thyroid carcinoma (FMTC).The MEN2 and FMTC syndromes involve different germline activating mutations in the RET proto-oncogene. Additionally, 40% to 50% of sporadic MTC specimens have acquired RET mutations.Ref: Sabiston 20e, page no: 932
Category:
Surgery
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now