The drug Vorapaxar acts by primarily inhibiting Platelet aggregation caused by which of the following substance ?

Correct Answer: Thrombin
Description: VORAPAXAR: MOA : Inhibits PAR-1 receptors leading to Anti-Platelet action. On the surface of the platelets, PAR-1 receptors are present, Thrombin binds to this receptor and result in activation of platelets, so drugs are developed to inhibit this PAR-1 receptor leading Anti-Platelet action by inhibiting aggregation caused by Thrombin.
Category: Pharmacology
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