The cycle of malaria parasite is in sequence of –
## Core Concept
The life cycle of the malaria parasite involves several stages and requires two hosts: the human and the mosquito. The stages in humans include the liver stage (exo-erythrocytic schizogony), the erythrocytic stage (blood stage), and in mosquitoes, it includes the gamete formation, zygote formation, and sporozoite formation.
## Why the Correct Answer is Right
The correct sequence of the malaria parasite's life cycle in humans is:
- The sporozoites infect the liver cells (liver stage).
- Then, the merozoites released from the liver infect red blood cells (erythrocytic stage).
- Within red blood cells, the parasites develop into trophozoites, schizonts, and then merozoites, causing the cells to rupture.
- Some parasites develop into gametocytes, which are the sexual stages.
## Why Each Wrong Option is Incorrect
- **Option A:** This option is incorrect because it does not accurately represent the sequence of the malaria parasite's life cycle.
- **Option B:** This option is incorrect as it also does not correctly sequence the stages of the malaria parasite's life cycle.
- **Option D:** This option is incorrect because it inaccurately represents the sequence and stages of the malaria parasite's life cycle.
## Clinical Pearl / High-Yield Fact
A key point to remember is that **Plasmodium vivax and Plasmodium ovale** have a dormant liver stage (hypnozoites), which can reactivate months to years later, leading to relapse. This is a critical distinction in the management and understanding of malaria.
## Correct Answer Line
**Correct Answer: C.**