Biochemistry The cause of hyperuricemia and gout in glucose-6-phosphatase deficiency is: A More formation of ribose 5-phosphate B Decreased availability of glucose to tissues C Increased accumulation of sorbitol D Impaired degradation of free radicals 💡 Explanation The cause of hyperuricemia and gout in glucose-6-phosphatase deficiency is: ✓ Correct Answer: A. More formation of ribose 5-phosphate