The antiepileptic drug which causes weight loss:
Correct Answer: Topiramate
Description: (Ref: Katzung 14th ed. pg. 427-28)* The only antiepileptic drug which causes weight loss: Topiramate, Zonisamide* MOA of topiramate:# VG-Na+ channel blocker# Activate GABA receptor# Inhibit AMPA receptor (receptor of Glutamate)* Use:# GTCS, Partial seizure# Maintenance therapy of alcohol withdrawal# LGS# Decreases alcohol craving* Side effects: Urolithiasis, Somnolence
Category:
Pharmacology
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