Biochemistry The activity of which of the following enzymes is directly affected by citrate? A Fructose-2,6-bisphosphatase B Isocitrate dehydrogenase C Phosphofructokinase I D Pyruvate carboxylase 💡 Explanation The activity of which of the following enzymes is directly affected by citrate? ✓ Correct Answer: C. Phosphofructokinase I