**Core Concept**
Tyrosine tRNA analogues are used in molecular biology to study protein synthesis and translation. One such analogue, aminoglycoside antibiotics, can cause premature chain termination by binding to the ribosome and inducing misreading of the mRNA template.
**Why the Correct Answer is Right**
The correct answer is a type of aminoglycoside antibiotic, specifically puromycin. Puromycin works by binding to the ribosome and inducing premature termination of protein synthesis. This occurs because puromycin is a tyrosine tRNA analogue that can be incorporated into the growing peptide chain, causing the ribosome to release the completed chain prematurely. This process is similar to the way in which a stop codon is recognized by a release factor, leading to termination of protein synthesis.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because it is not a known tyrosine tRNA analogue that causes premature chain termination.
* **Option B:** This option is incorrect because it is a different class of antibiotic that works by inhibiting protein synthesis, but not through premature chain termination.
* **Option D:** This option is incorrect because it is a type of antibiotic that works by inhibiting protein synthesis, but not through premature chain termination.
**Clinical Pearl / High-Yield Fact**
Aminoglycoside antibiotics, including puromycin, can cause premature chain termination and are often used in molecular biology to study protein synthesis and translation.
**Correct Answer:** C. Puromycin is a tyrosine tRNA analogue that causes premature chain termination.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.