Temporal arteritis all are associated except –
**Core Concept**
Temporal arteritis, also known as giant cell arteritis, is a chronic inflammatory condition affecting the medium and large arteries, particularly those in the head. It is characterized by granulomatous inflammation of the arterial wall, leading to stenosis and potentially life-threatening complications.
**Why the Correct Answer is Right**
Temporal arteritis is classically associated with polymyalgia rheumatica, a condition that presents with stiffness and pain in the shoulders and hips. The inflammation in temporal arteritis is thought to be mediated by the activation of CD4+ T cells and macrophages, which leads to the production of pro-inflammatory cytokines and the eventual destruction of the arterial wall. The condition is also associated with an increased risk of visual loss due to anterior ischemic optic neuropathy.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because while temporal arteritis is not typically associated with hypertension, it is often linked with other systemic inflammatory conditions such as polymyalgia rheumatica.
**Option B:** This option is incorrect because temporal arteritis is not typically associated with hyperlipidemia, although atherosclerosis is a common comorbidity in patients with temporal arteritis.
**Option C:** This option is incorrect because temporal arteritis is not typically associated with rheumatoid arthritis, although both conditions are examples of autoimmune disorders.
**Clinical Pearl / High-Yield Fact**
Temporal arteritis is a medical emergency that requires prompt treatment with corticosteroids to prevent visual loss and other complications.
**Correct Answer:** D.