**Core Concept**
Measles vaccine is a live attenuated vaccine that requires precise storage conditions to maintain its potency and efficacy. The storage temperature of the vaccine is critical in preventing degradation and ensuring its safety for administration.
**Why the Correct Answer is Right**
The measles vaccine should be stored at a temperature between 2°C and 8°C. This refrigerated temperature range is essential for preserving the live attenuated virus, which can be easily inactivated by temperatures above 25°C or below -15°C. The vaccine vial monitor (VVM) or the expiration date can be used to verify the vaccine's potency and stability within the recommended storage conditions.
**Why Each Wrong Option is Incorrect**
**Option A:** -15°C to 0°C is incorrect because temperatures below 2°C can cause the vaccine to become unstable and lose its potency.
**Option B:** 22°C to 25°C is incorrect because temperatures above 8°C can cause the vaccine to degrade rapidly, leading to a loss of efficacy.
**Option C:** Room temperature (20°C to 25°C) is incorrect because this temperature range is not suitable for storing live attenuated vaccines like the measles vaccine.
**Clinical Pearl / High-Yield Fact**
It is essential to check the vaccine vial monitor (VVM) or the expiration date to ensure the vaccine has not been exposed to temperatures that could compromise its stability and efficacy.
**Correct Answer:** C. 2°C to 8°C.
Free Medical MCQs · NEET PG · USMLE · AIIMS
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