Tangier’s disease is characterized by:
Correct Answer: Low or absence of HDL
Description: Tangier's disease/ Familial alpha-lipoprotein deficiency/Hypo alpha lipoproteinemia. Defect in ABC-A 1 receptors which helps in giving cholesterol from peripheral tissue to HDL. HDL is not properly formed- HDL | Other lipoproteins are normal. | Apo A1. Cholesterol accumulates in reticulo endothelial system C/F : Peripheral neuropathy, Hepatosplenomegaly Large orange/ yellow tonsils.
Category:
Biochemistry
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