**Core Concept**
The T4:T8 ratio is an indicator of the immune response, particularly in the context of periodontal diseases like gingivitis. **T helper cells (T4)** and **T suppressor cells (T8)** play crucial roles in the immune system.

**Why the Correct Answer is Right**
In gingivitis, there's an increase in the T4:T8 ratio, indicating a heightened immune response. This is because T4 cells are involved in activating the immune response, while T8 cells help in suppressing it. An increased ratio suggests a dominant helper T cell response.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not accurately reflect the immune response in gingivitis.
**Option B:** Similarly, this option does not align with the expected T4:T8 ratio in gingivitis.
**Option D:** This option also does not correctly represent the T4:T8 ratio associated with gingivitis.

**Clinical Pearl / High-Yield Fact**
A key point to remember is that an increased T4:T8 ratio is associated with active immune responses, which can be seen in various inflammatory conditions, including gingivitis.

**Correct Answer:** C. > 1