**Core Concept**
Glycine is a non-essential amino acid that can be synthesized in the body through various pathways. It is the simplest amino acid and serves as a precursor for the synthesis of purines, glutathione, and other important molecules.
**Why the Correct Answer is Right**
Glycine can be synthesized from threonine through the enzyme threonine aldolase, from serine through the enzyme serine hydroxymethyltransferase, and from hydroxyproline through the enzyme hydroxyprolinuria. Additionally, glycine can be synthesized from creatine through the enzyme creatininase, and from sarcosine through the enzyme sarcosine dehydrogenase.
**Why Each Wrong Option is Incorrect**
**Option A:** There is no known direct pathway for glycine synthesis from this compound.
**Option B:** This is actually a known pathway for glycine synthesis.
**Option C:** This is also a known pathway for glycine synthesis.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that glycine plays a crucial role in the synthesis of purines, which are the building blocks of DNA and RNA. A deficiency in glycine synthesis can lead to purine metabolism disorders, such as gout.
**Correct Answer: A.**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.