**Core Concept**
Cushing syndrome is a disorder caused by excess levels of cortisol in the body, leading to various physiological and pathological changes. This condition can result from endogenous (internal) causes, such as a pituitary tumor, or exogenous (external) causes, such as long-term glucocorticoid therapy.
**Why the Correct Answer is Right**
Cushing syndrome is characterized by **hypercortisolism**, which affects multiple systems in the body. One of the key features is **central obesity**, which is a result of fat redistribution, particularly in the abdominal area. This is due to the effects of cortisol on adipose tissue and the distribution of body fat. Additionally, patients with Cushing syndrome often exhibit **hypertension**, **hyperglycemia**, and **hypokalemia** due to the mineralocorticoid effects of cortisol. **Hirsutism** and **male pattern baldness** in females are also common due to the androgenic effects of cortisol.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incomplete and cannot be evaluated.
**Option B:** This option is not specific to Cushing syndrome and can be seen in various other conditions.
**Option C:** This option is incorrect as it is more frequently associated with hypothyroidism.
**Clinical Pearl / High-Yield Fact**
In Cushing syndrome, the **"moon face"** and **"buffalo hump"** are classic signs of hypercortisolism due to fat redistribution in the body.
**Correct Answer: D.**
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