Which cranial nerve is not transmitted by superior orbital fissure?

**Core Concept**
The superior orbital fissure is a complex anatomical structure that allows the passage of several cranial nerves and other structures between the orbit and the cranial cavity. Understanding the nerves transmitted through this fissure is crucial for diagnosing and managing various ophthalmological and neurological conditions.

**Why the Correct Answer is Right**
The correct answer is the cranial nerve that does not pass through the superior orbital fissure. The nerves that do pass through the superior orbital fissure include the oculomotor nerve (III), the trochlear nerve (IV), the abducens nerve (VI), the ophthalmic division of the trigeminal nerve (V1), and the first two divisions of the oculomotor nerve (V2), and the nasociliary nerve (V3), along with the sympathetic fibers from the superior cervical ganglion. These nerves are responsible for controlling the movement of the eye, eyelid, and eyelid muscles, as well as sensory innervation of the eye and surrounding tissues.

**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because the oculomotor nerve (III) is indeed transmitted through the superior orbital fissure.
* **Option B:** This option is incorrect because the trochlear nerve (IV) also passes through the superior orbital fissure.
* **Option C:** This option is incorrect because the abducens nerve (VI) is also transmitted through the superior orbital fissure.
* **Option D:** This option is incorrect because the ophthalmic division of the trigeminal nerve (V1) is indeed transmitted through the superior orbital fissure.

**Clinical Pearl / High-Yield Fact**
The superior orbital fissure is often referred to as the "keyhole" of the orbit, and its contents are closely related to the structures of the anterior cranial fossa. Knowledge of the nerves transmitted through this fissure is crucial for diagnosing and managing conditions such as superior orbital fissure syndrome, which can result from trauma, tumors, or other lesions affecting the nerves and surrounding tissues.

**Correct Answer:** D.