Supercarrier of hepatitis B shows positive for
**Core Concept**
The term "supercarrier" of hepatitis B refers to individuals who have a high viral load and are highly infectious, often without exhibiting symptoms. This phenomenon is associated with specific viral markers that indicate active replication of the virus.
**Why the Correct Answer is Right**
The correct answer is related to the presence of HBeAg (Hepatitis B e-antigen), which is a protein produced by the hepatitis B virus during active replication. HBeAg is a marker of viral replication and is often found in the serum of individuals with high viral loads, making them supercarriers. The presence of HBeAg is associated with increased infectivity and a higher risk of disease transmission.
**Why Each Wrong Option is Incorrect**
**Option A:** HBsAg (Hepatitis B surface antigen) is a marker of infection but does not necessarily indicate active replication or high viral load.
**Option B:** Anti-HBc (Antibody to hepatitis B core antigen) indicates exposure to the virus but does not necessarily indicate active replication.
**Option C:** Anti-HBs (Antibody to hepatitis B surface antigen) indicates immunity to the virus, either from vaccination or past infection.
**Clinical Pearl / High-Yield Fact**
The presence of HBeAg in a patient with hepatitis B infection is a strong indicator of high viral load and increased infectivity, emphasizing the need for strict infection control measures.
**Correct Answer: B. Anti-HBe (Antibody to hepatitis B e-antigen)**