## **Core Concept**
The patient's presentation suggests a renal condition following a streptococcal infection, indicated by a sore throat. The symptoms of hematuria, proteinuria, hypertension, and low serum complement C3 levels point towards a specific type of glomerulonephritis.
## **Why the Correct Answer is Right**
The clinical presentation of this patient, including the recent history of sore throat (suggestive of a post-streptococcal infection), sudden onset of hematuria, generalized edema, hypertension, proteinuria, red cell casts in the urine, deranged renal function tests (RFTs), and low levels of serum complement C3, is highly suggestive of **Post-Streptococcal Glomerulonephritis (PSGN)**. PSGN typically occurs after a streptococcal infection, such as strep throat. The condition is characterized by the deposition of immune complexes in the glomeruli, leading to inflammation. The low serum C3 level is a hallmark of PSGN, as C3 is consumed during the immune complex formation and activation of the complement system.
## **Why Each Wrong Option is Incorrect**
- **Option A:** This option is incorrect because it does not match the clinical presentation described. Without a specific description of the histological findings for each option, we can infer based on common knowledge of renal pathology.
- **Option B:** This option is incorrect for similar reasons; it does not align with the expected histological findings in PSGN.
- **Option D:** This option is incorrect as it does not represent the typical histological findings associated with PSGN.
## **Clinical Pearl / High-Yield Fact**
A key clinical pearl in this scenario is that PSGN often presents with **low serum C3 levels** during the acute phase, which typically returns to normal within 8-12 weeks. This differentiates it from other causes of glomerulonephritis that may present with persistently low C3 levels, such as membranoproliferative glomerulonephritis.
## **Correct Answer:** . **Proliferative Glomerulonephritis**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.