**Core Concept**
Succinylcholine is a depolarizing neuromuscular blocking agent that can trigger malignant hyperthermia (MH) and cause hyperkalemia by releasing potassium from muscle cells. It is also known to cause anaphylaxis and histamine release in some patients.
**Why the Correct Answer is Right**
Succinylcholine is used with caution in patients with a history of malignant hyperthermia, burns, spinal cord injuries, and those with muscular dystrophies. This is because these conditions can increase the risk of hyperkalemia and malignant hyperthermia. The drug can also cause hyperkalemia in patients with renal failure due to impaired potassium excretion.
**Why Each Wrong Option is Incorrect**
**Option A:** Patients with renal failure are at increased risk of succinylcholine-induced hyperkalemia due to impaired potassium excretion.
**Option B:** Patients with muscular dystrophies are at increased risk of succinylcholine-induced hyperkalemia and malignant hyperthermia due to muscle cell damage and increased susceptibility to MH.
**Option C:** Patients with spinal cord injuries are at increased risk of succinylcholine-induced hyperkalemia and malignant hyperthermia due to muscle atrophy and denervation.
**Clinical Pearl / High-Yield Fact**
Succinylcholine can cause a significant increase in potassium levels, which can lead to cardiac arrhythmias and even cardiac arrest. This is why it is essential to monitor potassium levels and ECGs closely in patients receiving succinylcholine.
**Correct Answer: D. A patient with a normal airway and no history of malignant hyperthermia or other contraindications.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.