Substrate-level phosphorylation seen in reaction catalysed in
Correct Answer: Succinyl CoA thiokinase
Description: 5th Step of TAC CYCLE: Generation of Succinate The next reaction involves a substrate level phosphorylation whereby a high energy phosphate is generated from the energy trapped in the thioester bond of succinyl CoA. The enzyme is succinate thiokinase (step 5, Fig.18.2). A molecule of GDP is phosphorylated to GTP and succinate is formed. The GTP can be conveed to ATP by reacting with an ADP molecule: GTP + ADP - GDP + ATPRef: DM Vasudevan Textbook of Medical Biochemistry, 6th edition, page no: 218
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