Substance ideal for GFR estimation is?
Correct Answer: Inulin clearance
Description: Ans: a (Inulin clearance)^/: Ganong, 22nd ed,p. 706GFR can be measured in intact experimental animals and humans by measuring the excretion and plasma level of a substance that is freely filtered through the glomeruli and neither secreted nor reabsorbed in the tubules.Inulin is a polymer of fructose with a molecular weight of 5200 obtained from Dahlia tubers, meets the above criterion and is extensively used to measure GFR.Remember Ideal substance to measure GFR-InulinSubstance used for practical purposes-CreatinineSubstance used to measure renal blood flow-PAHNormal GFR of human beings-125 ml/min ClearanceCx=UVP=Urine concentrationsne flow/time (V)Plasma concentration.
Category:
Physiology
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