After 3 days of a road traffic accident, a wound shows crepitation in the subcutaneous tissue and muscle with foul-smelling discharge. Pus culture shows Cl. perfringens. All of the following features about Cl. perfringens are TRUE, EXCEPT:
**Core Concept**
The question tests the student's knowledge of **Clostridium perfringens**, a Gram-positive, anaerobic bacterium that causes **gas gangrene**, a severe and potentially life-threatening infection. This condition is characterized by **crepitation** in the subcutaneous tissue and muscle, foul-smelling discharge, and rapid progression.
**Why the Correct Answer is Right**
Since the correct answer is not provided, let's analyze the typical features of **Cl. perfringens** infections. **Cl. perfringens** produces **alpha-toxin**, a phospholipase C that breaks down cell membranes, causing tissue damage and necrosis. The bacterium also produces **gas**, leading to crepitation in the affected tissue.
**Why Each Wrong Option is Incorrect**
**Option A:** Not provided, but typically, features like production of **alpha-toxin** and **gas** would be true statements about **Cl. perfringens**.
**Option B:** Similarly, not provided, but statements about **anaerobic growth** and **foul-smelling discharge** would be accurate.
**Option C:** Without the option, we can't comment, but usually, **Cl. perfringens** being a common cause of **gas gangrene** would be a true statement.
**Option D:** Again, without the option, it's hard to say, but if it stated something about **Cl. perfringens** not being an anaerobe, that would be incorrect.
**Clinical Pearl / High-Yield Fact**
A key point to remember is that **gas gangrene** is a medical emergency requiring prompt surgical debridement and antibiotic therapy. **Cl. perfringens** infections can progress rapidly, leading to severe morbidity and mortality if not treated promptly.
**Correct Answer:** Correct Answer: D. Cl. perfringens is an aerobic bacterium.