**Core Concept**
Streptococcal toxic shock syndrome (STSS) is a severe condition caused by the release of bacterial toxins from Group A beta-hemolytic Streptococcus (GABHS). This syndrome is characterized by fever, hypotension, and multi-organ failure.
**Why the Correct Answer is Right**
Pyrogenic exotoxins, also known as erythrogenic toxins, are produced by GABHS and are responsible for the systemic symptoms of STSS. These toxins are superantigens that can induce a massive release of cytokines, leading to the clinical manifestations of the syndrome. The pyrogenic exotoxins stimulate T cells, causing an overwhelming immune response and subsequent tissue damage.
**Why Each Wrong Option is Incorrect**
**Option A:** TSS-1 is not a recognized term in the context of streptococcal toxic shock syndrome.
**Option B:** Enterotoxins are associated with staphylococcal food poisoning and are not the primary cause of STSS.
**Option D:** Endotoxins are components of the outer membrane of gram-negative bacteria and are not produced by GABHS.
**Clinical Pearl / High-Yield Fact**
It's essential to recognize the clinical presentation of STSS, which can include fever, hypotension, renal failure, and respiratory distress. Prompt recognition and treatment with antibiotics and supportive care are critical to improving outcomes.
**β Correct Answer: C. Pyrogenic exotoxin**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.