**Core Concept**
Streptococcal Toxic Shock Syndrome (STSS) is a life-threatening condition caused by Streptococcus pyogenes, a Group A beta-hemolytic streptococcus (GABHS). It is characterized by fever, hypotension, and multi-organ failure due to the production of a potent exotoxin.
**Why the Correct Answer is Right**
The correct answer is due to the production of Streptolysin O (SLO), a thiol-activated, oxygen-labile exotoxin produced by Streptococcus pyogenes. SLO causes cell lysis by forming a pore in the cell membrane, leading to the release of cellular contents and the formation of a shock-like syndrome. This toxin also inactivates the complement system, contributing to the pathogenesis of STSS.
**Why Each Wrong Option is Incorrect**
* **Option A:** While erythrogenic toxins (also known as pyrogenic exotoxins) are responsible for the rash in Scarlet fever, they are not the primary virulence factor in STSS.
* **Option B:** Hyaluronic acid capsule is a virulence factor for Streptococcus pyogenes, but it is not directly involved in the pathogenesis of STSS.
* **Option D:** Lipoteichoic acid is a component of the cell wall of Gram-positive bacteria, including Streptococcus pyogenes, but it is not the primary virulence factor responsible for STSS.
**Clinical Pearl / High-Yield Fact**
Remember that STSS is a medical emergency that requires prompt recognition and treatment, often involving antibiotics, supportive care, and surgical interventions to manage complications.
**Correct Answer:** C. Streptolysin O (SLO)
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.