Street rabies virus cause –
**Question:** Street rabies virus cause
**Core Concept:** Rabies is a zoonotic neuroinvasive viral disease caused by the rabies virus. It primarily affects the central nervous system, leading to encephalitis and eventually, death if left untreated.
**Why the Correct Answer is Right:** The correct answer refers to the primary cause of street rabies, which is the rabies virus (Rabies virus). This virus belongs to the Lyssavirus genus within the family Rhabdoviridae. The virus primarily affects the central nervous system, causing rabies, which is characterized by a characteristic clinical syndrome known as the "mad dog" or "furious" form. Once the virus infiltrates the central nervous system, it leads to progressive neurological dysfunction, ultimately resulting in death if left untreated.
**Why Each Wrong Option is Incorrect:**
A. **Rabies bacteria (Rabies bacillus):** This incorrect answer refers to a misconception that rabies is caused by bacteria, which is incorrect. Rabies is primarily caused by the rabies virus.
B. **Rabies vaccination (Protective measures):** This option discusses the preventive measures, such as vaccination, which are used to protect against rabies, not the cause of the disease itself.
C. **Environmental factors (E.g., contaminated water):** While environmental factors can contribute to the transmission of rabies, the core cause remains the rabies virus.
D. **Rabies vaccination (Protective measures):** Similar to option B, this answer discusses preventive measures, not the cause of the disease.
**Clinical Pearl / High-Yield Fact:** Rabies is a highly fatal disease that can be prevented through timely vaccination and post-exposure prophylaxis (PEP). However, the primary cause of rabies is the rabies virus, which enters the body through an infected animal bite or, less commonly, through consumption of contaminated food. Once the virus enters the central nervous system, it leads to progressive neurological dysfunction and eventually death. The disease has a very high mortality rate without proper treatment.