Strain used in Mumps vaccine?
Correct Answer: Jeryl Lynn
Description: Ans. C. Jeryl Lynn. (Ref. Park's Textbook of PSM 22nd /pg. 144)The current mumps strain (Jeryl Lynn) has the lowest asso incidence of post vaccine aspectic meningitis.Discussion: VaccineStrain1MeaslesEdmonsten Zagreb2ChickenpoxOka3BCGDanish 13314RubellaRA 27/35MumpsJeryl Lynn, RIT 4385, Leningrad-3, L-Zagreb, Urabe, Hoshino, Torii, NKM-466TyphoidTy21a7Yellow fever17D8Japanese encephalitisNakayama, Beijing,, Beijing P-3, SA 14-14-29Brucellosis19- BA10LeprosyICRC bacillusMumps vaccine# Live attenuated mumps vaccine (Jeryl Lynn strain) induces antibodies that protect the recipient against infection in >95% of cases.# Mumps vaccine is usually administered as part of the measles-mumps-rubella (MMR) vaccine at the age of 12-15 months and again at 4--12 years of age.# MMR vaccine will probably be supplanted by MMRV vaccine, which also covers varicella.# Licensed by the U.S. Food and Drug Administration in 2005, MMRV is licensed for use only in children 1-13 years of age.# Vaccination is also recommended for susceptible older children, adolescents, and adults, particularly male adolescents who have not had mumps.# For these patients, either MMR or monovalent mumps vaccine may be given; two doses are preferred. Inadvertent immunization of individuals who are already immune is not associated with significant adverse reactions.# Mumps vaccine is not recommended for pregnant women, for patients receiving glucocorticoids, or for other immunocompromised hosts.# However, children with HIV infection who are not severely immunocompromised can safely be immunized against mumps; MMR vaccine is usually used for this purpose.# Occasionally, febrile reactions and parotitis have been reported soon after mumps vaccination. Allergic reactions after vaccination, such as rash and pruritus, occur uncommonly and are usually mild and self-limited.
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