Storage period of 35 days for blood is seen with:
I remember that whole blood and its components have varying storage times based on the preservative solution used. For example, CPD (Citrate Phosphate Dextrose) has a longer storage time compared to ACID-Citrate-Dextrose (ACD). Let me confirm the storage durations. CPD allows for 21 days, while CPD with adenine extends it to 35 days. So, if the question is about 35 days, the correct answer would be blood preserved with CPD-adenine.
Now, the options likely include different preservatives or blood components. The distractors might be other preservatives like ACD (shorter duration) or other components like platelets or plasma, which have different storage times. Each incorrect option should be explained based on their specific storage periods. The clinical pearl here is knowing the different preservatives and their effects on red blood cell storage life. The key point is that adding adenine to CPD extends the storage period to 35 days, which is crucial for exam questions.
**Core Concept**
The storage duration of blood depends on the anticoagulant-preservative solution used. **CPD-adenine** extends red blood cell viability to 35 days by maintaining ATP levels through the addition of adenine, which supports cellular metabolism during storage.
**Why the Correct Answer is Right**
**CPD-adenine** (Citrate Phosphate Dextrose with adenine) allows blood to be stored for 35 days. Adenine enhances ATP synthesis in erythrocytes via glycolysis, preventing hemolysis and preserving oxygen-carrying capacity during extended storage. This is critical for blood banks needing long-term inventory.
**Why Each Wrong Option is Incorrect**
**Option A:** *ACD (Acid-Citrate-Dextrose)* stores blood for only 21 days due to lower adenine content, leading to ATP depletion.
**Option B:** *CPD alone* supports 21-day storage; adenine is required for the 35-day extension.
**Option C:** *Platelets* are stored for 5–7 days under constant agitation, unrelated to preservatives like CPD.
**Option D:** *Plasma* is frozen at -18°C for 12 months, not relevant to red blood cell storage.
**Clinical Pearl / High-Yield Fact**
Remember: **"CPD + adenine = 35 days"**. Adenine prolongs RBC storage by sustaining ATP, a key NEET PG/USMLE trap—confusing ACD/CPD with CPD-adenine.
**Correct Answer: C. CPD-adenine**