Stimulation of ovary in the early follicular phase is by:
**Core Concept:**
The early follicular phase in the menstrual cycle is characterized by the growth and maturation of ovarian follicles, ultimately leading to ovulation. This process is regulated by the hypothalamic-pituitary-ovarian axis, which involves gonadotropin-releasing hormone (GnRH), luteinizing hormone (LH), and follicle-stimulating hormone (FSH).
**Why the Correct Answer is Right:**
The correct answer refers to the primary role of follicle-stimulating hormone (FSH) in the early follicular phase. FSH promotes the growth and maturation of ovarian follicles, ensuring the development of a dominant follicle that will eventually release an egg during ovulation. FSH stimulates the granulosa cells surrounding the follicle to produce estrogen, which in turn inhibits GnRH release from the hypothalamus.
**Why Each Wrong Option is Incorrect:**
A. Luteinizing hormone (LH) is involved in the late follicular phase, leading to ovulation, not in the early follicular phase.
B. Gonadotropin-releasing hormone (GnRH) stimulates the pituitary gland to release FSH and LH, but it is not directly involved in the early follicular phase process.
C. Both options A and B are correct, but they do not address the primary role of FSH in the early follicular phase.
**Clinical Pearl:**
Understanding the hormonal interactions and roles of FSH, LH, and GnRH is crucial for understanding the menstrual cycle and fertility. A thorough knowledge of these hormones allows for proper diagnosis and treatment of disorders related to the hypothalamic-pituitary-ovarian axis, such as polycystic ovary syndrome (PCOS) and menstrual irregularities.
**Correct Answer:**
D. Follicle-stimulating hormone (FSH)
**Explanation:**
FSH plays a crucial role in the early follicular phase, stimulating the growth and maturation of ovarian follicles. It is essential for the development of a dominant follicle that will eventually release an egg during ovulation. The role of FSH during this phase contrasts with that of LH (which is involved in ovulation) and GnRH (which stimulates the pituitary gland to release FSH and LH).