**Core Concept**
Vigabatrin is an antiepileptic medication that acts by inhibiting the breakdown of gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the central nervous system.

**Why the Correct Answer is Right**
Vigabatrin works by irreversibly inhibiting the enzyme GABA transaminase, which is responsible for degrading GABA in the synaptic cleft. This leads to an accumulation of GABA, resulting in increased inhibitory neurotransmission. However, one of the notable side effects of vigabatrin is its potential to cause visual field defects, including concentric visual field loss, as it can lead to damage to the retinal ganglion cells. This is a well-documented and dose-dependent side effect of vigabatrin.

**Why Each Wrong Option is Incorrect**
**Option A:** Vigabatrin does not act by blocking the neuronal reuptake of GABA; rather, it inhibits the breakdown of GABA.
**Option B:** Vigabatrin is not typically considered a first-line treatment for absence seizures; other medications such as valproate or ethosuximide are more commonly used.
**Option C:** While vigabatrin can cause a range of skin-related side effects, life-threatening skin disorders are not typically associated with its use.

**Clinical Pearl / High-Yield Fact**
It is essential for clinicians to monitor patients taking vigabatrin for visual field defects, particularly at regular intervals, as this can impact the patient's quality of life and even lead to vision loss in severe cases.

**✓ Correct Answer: D. Visual disturbances can occur**