**Core Concept**
Digitoxin is a cardiac glycoside used in the treatment of heart failure and atrial fibrillation. It works by inhibiting the sodium-potassium ATPase pump, leading to an increase in intracellular calcium and a subsequent increase in myocardial contractility.
**Why the Correct Answer is Right**
Digitoxin has a longer half-life compared to digoxin, which requires less frequent dosing. It also has a higher lipid solubility, allowing it to cross the blood-brain barrier and potentially causing central nervous system toxicity. This unique pharmacokinetic profile makes digitoxin a valuable treatment option for certain patients. The inhibition of the sodium-potassium ATPase pump by digitoxin leads to an increase in intracellular calcium, which in turn enhances the contractility of the myocardium.
**Why Each Wrong Option is Incorrect**
**Option A:** This statement is not provided, so we cannot evaluate its accuracy.
**Option B:** This statement is not provided, so we cannot evaluate its accuracy.
**Option C:** This statement is not provided, so we cannot evaluate its accuracy.
**Option D:** This statement is not provided, so we cannot evaluate its accuracy.
**Clinical Pearl / High-Yield Fact**
It's essential to note that digitoxin has a narrow therapeutic index, and its toxicity can be unpredictable. Monitoring of serum levels and close clinical observation are crucial to avoid adverse effects.
**Correct Answer:**
(D)
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