## Core Concept
Articular cartilage undergoes various changes with aging, affecting its structure and function. These changes include alterations in the composition and organization of the cartilage matrix, which is primarily made up of collagen, proteoglycans, and water. The aging process can lead to a decrease in the thickness and integrity of the articular cartilage.

## Why the Correct Answer is Right
The correct statement regarding changes in articular cartilage with aging involves an understanding of the specific alterations that occur. Typically, with aging, articular cartilage exhibits:
- A decrease in the synthesis of new proteoglycans and collagen.
- An increase in the degradation of these matrix components.
- A reduction in the water content of the cartilage.

However, without the specific options provided, we'll proceed to analyze the incorrect statements based on common knowledge about articular cartilage aging.

## Why Each Wrong Option is Incorrect
Given that the specific details of options A, B, C, and D are not provided, let's discuss general incorrect statements about articular cartilage changes with aging:

- **Option A:** If a statement claims that articular cartilage thickness increases with age, it would be incorrect because aging typically leads to a decrease in cartilage thickness.
- **Option B:** If a statement suggests that the water content of articular cartilage increases with age, it would be incorrect because the water content generally decreases.
- **Option C:** If a statement posits that there is an increase in the synthesis of proteoglycans and collagen with aging, it would be incorrect as aging is associated with decreased synthesis of these components.
- **Option D:** This would be the correct statement, which we're trying to identify as not being true based on the question.

## Clinical Pearl / High-Yield Fact
A key point to remember is that **aging leads to a reduction in the thickness and an increase in the stiffness of articular cartilage**, primarily due to changes in the matrix composition, such as decreased proteoglycan content and altered collagen structure. This can predispose individuals to conditions like osteoarthritis.

## Correct Answer: D.