Pathology All of the following statement are true regarding silicosis, except: A Crystalline forms are much more fibrogenic B Phagocytosed silica crystals activate the inflammasome, leading to the release of inflammatory mediators, paicularly IL-2 and TNF C As the disease progresses, nodules coalesce into hard, collagenous scars D Histologic examination reveals the hallmark lesion characterized by a central area of whorled collagen fibers with a more peripheral zone of dust-laden macrophages. 💡 Explanation All of the following statement are true regarding silicosis, except: ✓ Correct Answer: B. Phagocytosed silica crystals activate the inflammasome, leading to the release of inflammatory mediators, paicularly IL-2 and TNF